Heart failure is a major public health problem. Despite recent favourable trends in survival, heart failure remains highly fatal with an average life expectancy of about three years following diagnosis. This Essential CPE covers the signs and symptoms of heart failure, diagnosis and management, as well as implications for pharmacists. Pathophysiology of heart failure Diagnosis of heart failure Signs and symptoms of heart failure Pharmacological management of heart failure Complementary therapies for heart failure Non-pharmacological management of heart failure