Determinants of trajectories of multi-site pain in knee osteoarthritis: a 10.7-year prospective study in older adults

Pain in osteoarthritis (OA) is very common especially in elderly and commonly occurs at multiple sites. Multi-site pain (MSP) has been shown to be associated with more severe symptoms and worse health-related quality of life compared to single-site pain. Limited evidence exists about understanding the course of MSP and its determinants.

Objectives: To identify distinct trajectories of MSP over 10.7 years in an older population, and to examine risk factors for identified trajectories