Modelling damaged lung pressure–volume behaviour

This paper investigates the performance of a model of time dependent lung pressure-volume behaviour when applied to experimental data from neonatal piglets. The model was built using Labview and applied to experimental dynamic recruitment data from the previously published studies of other researchers. The experimental data featured multiple tidal pressure-volume loops during inflation and deflation to/from total lung capacity (TLC) respectively, but the model was not able to replicate these satisfactorily. Model performance was substantially poorer during deflation from TLC (deflation limb) than during inflation to TLC (Inflation limb). Ideas are discussed for improving the model.