An analysis of symmetric function theory is given from the perspective of the underlying Hopf and bi-algebraic structures. These are presented explicitly in terms of standard symmetric function operations. Particular attention is focused on Laplace pairing, Sweedler cohomology for 1- and 2-cochains and twisted products (Rota cliffordizations) induced by branching operators in the symmetric function context. The latter are shown to include the algebras of symmetric functions of orthogonal and symplectic type. A commentary on related issues in the combinatorial approach to quantum field theory is given.