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A mechanistic study on the oxidation of hydrazides: application to the tuberculosis drug isoniazid

journal contribution
posted on 2023-05-16, 23:11 authored by Amos, RIJ, Gourlay, BS, Schiesser, CH, Jason SmithJason Smith, Brian YatesBrian Yates
Herein we report radical trapping experiments that support the formation of an acyl radical as the active species from the oxidation of isoniazid; these data provide insight into the mechanism of hydrazide oxidation. © The Royal Society of Chemistry.

History

Publication title

Chemical Communications

Volume

2008

Issue

14

Pagination

1695-1697

ISSN

1359-7345

Department/School

School of Natural Sciences

Publisher

The Royal Society of Chemistry

Place of publication

Cambridge

Rights statement

Copyright 2008 The Royal Society of Chemistry

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  • Restricted

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