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Age, muscle fatigue, and walking endurance in pre-menopausal women
journal contribution
posted on 2023-05-18, 21:32 authored by Hunter, GR, Bickel, CS, Del Corral, P, Nuala ByrneNuala Byrne, Andrew HillsAndrew Hills, Larson-Meyer, DE, Banman, MM, Newcomer, BRAging is associated with loss of endurance; however, aging is also associated with decreased fatigue during maximal isometric contractions. The aims of this study were to examine the relationship between age and walking endurance (WE) and maximal isometric fatigue (MIF) and to determine which metabolic/fitness components explain the expected age effects on WE and MIF. Subjects were 96 pre-menopausal women. Oxygen uptake (walking economy) was assessed during a 3-mph walk; aerobic capacity and WE by progressive treadmill test; knee extension strength by isometric contractions, MIF during a 90-s isometric plantar flexion (muscle metabolism measured by 31P MRS). Age was related to increased walking economy (low VO2, r = −0.19, P < 0.03) and muscle metabolic economy (force/ATP, 0.34, P = 0.01), and reduced MIF (−0.26, P < 0.03). However, age was associated with reduced WE (−0.28, P < 0.01). Multiple regression showed that muscle metabolic economy explained the age-related decrease in MIF (partial r for MIF and age −0.13, P = 0.35) whereas walking economy did not explain the age-related decrease in WE (partial r for WE and age −0.25, P < 0.02). Inclusion of VO2max and knee endurance strength accounted for the age-related decreased WE (partial r for WE and age = 0.03, P > 0.80). In premenopausal women, age is related to WE and MIF. In addition, these results support the hypothesis that age-related increases in metabolic economy may decrease MIF. However, decreased muscle strength and oxidative capacity are related to WE.
History
Publication title
European Journal of Applied PhysiologyVolume
111Issue
4Pagination
715-723ISSN
1439-6319Department/School
School of Health SciencesPublisher
Springer-VerlagPlace of publication
United StatesRights statement
Copyright 2010 Springer-VerlagRepository Status
- Restricted