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An Algebraic Model of RNA Duplex Formation
We propose a simple algebraic description of the two-body interactions of bases in RNA thermodynamics showing in detail qualitative equivalence with conventional nearest-neighbor models. The process of obtaining base content, polymer, and oligomer parameters is illustrated, and for duplexes containing Watson-Crick pairs, fits to oligonucleotide duplex heat-of-formation data are shown to be statistically equivalent to existing models. © 2004 Wiley Periodicals, Inc.
History
Publication title
BiopolymersVolume
73Issue
6Pagination
657-667ISSN
0006-3525Department/School
School of Natural SciencesPublisher
John Wiley & Sons IncPlace of publication
Hoboken, USARepository Status
- Restricted