Anti-biogram and resistogram profiling of aeromonas species isolated from Malaysian coastal seawater

Antibiotics and heavy metals resistance profile of Aeromonas species isolated from Kuala Gula and Kuala Sepetang, Perak, was investigated in this study.Isolated Aeromonas species were subjected to 12 antibiotics: Penicillin G 10 units, Tetracycline 30 µg, Novobiocin 5 µg, Nitrofurantoin 100 µg, Ampicillin 10 µg, Chloramphenicol 10 µg, Fluconazole 25 µg, Gentamicin 10 µg, Streptomycin 10 µg and 25 µg, Kanamycin30 µg, and Vancomycin 30 µg and 5 heavy metals: MnSO (_4 ).H (_2 )O; Cr(NO (_3 )).9H (_2 )O; CuSO (_4 ); Pb (NO (_3 )) (_2 ); HgCl (_2 ). Results from this study revealed that-isolates from the two sources-displayed varied resistance. Isolates from Kuala Sepetang showed 91%, 66%, 61%, and 52 % to Vancomycin, Novobiocin, Streptomycin-and Gentamycin while Kuala Gula isolates showed 76%, 93%, 28% and 14 % respectively. High rate of resistance to lead (Pb), Chromium (Cr), copper (Cu) and Manganese (Mn) with minimum inhibitory concentration ranging from 2560µg/mL to >5120 µg/mL. Low resistance to mercury was observed among isolates from Kuala Gula.This study showed that there was widespread of both heavy metals and antibiotics resistance among Aeromonas isolates in coastal seawater from Kuala Sepetang showing more resistance thereby posing danger to both aquatic animals and human health.