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Aortic pulsatility drives microvascular organ damage in essential hypertension: New evidence from choroidal thickness assessment

journal contribution
posted on 2023-05-22, 01:34 authored by Bruno, RM, Rachel ClimieRachel Climie, Gallo, A
In a healthy cardiovascular system, the compliant properties of the large arteries ensure that pulsations in pressure and flow generated by cyclic left ventricular contraction are dampened at the site of the ascending aorta into a continuous pressure (and flow) downstream at the site of arterioles. This allows for the delivery of a steady flow of blood during organ perfusion, and the microvasculature of target organs is protected from the damaging effects of pressure pulsatility.

Funding

Heart Foundation

History

Publication title

Journal of Clinical Hypertension

Volume

23

Issue

5

Pagination

1039-1040

ISSN

1524-6175

Department/School

Menzies Institute for Medical Research

Publisher

John Wiley & Sons, Inc.

Place of publication

United States

Repository Status

  • Restricted

Socio-economic Objectives

Prevention of human diseases and conditions

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