University Of Tasmania
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Applications of transcranial direct current stimulation in children and pediatrics

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journal contribution
posted on 2023-05-19, 01:50 authored by Rivera-Urbina, GN, Nitsche, MA, Vicario, CM, Molero-Chamizo, A
Transcranial direct current stimulation (tDCS) is a neuromodulatory noninvasive brain stimulation tool with potential to increase or reduce regional and remote cortical excitability. Numerous studies have shown the ability of this technique to induce neuroplasticity and to modulate cognition and behavior in adults. Clinical studies have also demonstrated the ability of tDCS to induce therapeutic effects in several central nervous system disorders. However, knowledge about its ability to modulate brain functions in children or induce clinical improvements in pediatrics is limited. The objective of this review is to describe relevant data of some recent studies that may help to understand the potential of this technique in children with specific regard to effective and safe treatment of different developmental disorders in pediatrics. Overall, the results show that standard protocols of tDCS are well tolerated by children and have promising clinical effects. Nevertheless, treatment effects seem to be partially heterogeneous, and a case of a seizure in a child with previous history of infantile spasms and diagnosed epilepsy treated with tDCS for spasticity was reported. Further research is needed to determine safety criteria for tDCS use in children and to elucidate the particular neurophysiological changes induced by this neuromodulatory technique when it is applied in the developing brain.


Publication title

Reviews in the Neurosciences








School of Psychological Sciences


Freund & Pettman Publishers

Place of publication

United Kingdom

Rights statement

Copyright © 2016 by Walter de Gruyter GmbH

Repository Status

  • Restricted

Socio-economic Objectives

Neonatal and child health