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Approaches to enhancing the sensitivity of capillary electrophoresis methods for the determination of inorganic and small organic anions
journal contributionposted on 2023-05-16, 12:58 authored by Michael BreadmoreMichael Breadmore, Paul HaddadPaul Haddad
One of the major problems facing the development of capillary electrophoresis (CE) is the relatively high limits of detection when compared to traditional high-performance liquid chromatographic (HPLC) methods. While the use of an alternative detector can offer better sensitivity, a more universal approach is sample preconcentration. Numerous on-line methods have been developed to improve the sensitivity of CE, and are based on electrophoretic principles, chromatographic principles, or a combination of both. This review will discuss all forms of on-line preconcentration methods for CE, with emphasis given to those that have shown particular merit when applied to inorganic and small organic anions.
Department/SchoolSchool of Natural Sciences
PublisherWiley-VCH Verlag GmbH
Place of publicationBerlin, Germany
Rights statementThe definitive published version is available online at: http://interscience.wiley.com