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Autoradiographic localisation of substance P (NK1) receptors in human primary visual cortex
journal contribution
posted on 2023-05-16, 11:02 authored by Kus, L, Mazzone, SB, Paxinos, G, Dominic GeraghtyThis study utilised autoradiography to examine [125I]-Bolton Hunter substance P (BHSP) binding in postmortem human visual cortex. In the primary visual area, layers I-III, IVC and VI exhibited low levels of BHSP binding, while high levels were observed in layers IVB and V. Because cells in layers IVB and V are known to be involved in processing direction-specific stimuli, it is possible that SP plays a role in modulating this visual process.
History
Publication title
Brain ResearchVolume
794Pagination
309-312ISSN
0006-8993Department/School
School of Health SciencesPublisher
ElsevierPlace of publication
The NetherlandsRepository Status
- Restricted