Boron-Mediated Stereoselective Syntheses of γ,γ-Disubstituted Allenamides
journal contribution
posted on 2023-05-17, 08:39authored byHyland, CJT, Hegedus, LS
Propargylic boranes generated by lithiation of optically active N-propargyloxazolidinones undergo reaction with a range of aldehydes to produce γ,γ-disubstituted allenamides with good diastereoselectivity.