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Childhood socioeconomic status and arterial stiffness in adulthood: the cardiovascular risk in Young Finns Study

journal contribution
posted on 2023-05-19, 13:09 authored by Puolakka, E, Pahkala, K, Laitinen, TT, Costan Magnussen, Hutri-Kahaonen, N, Kahonen, M, Lehtimaki, T, Tossavainen, P, Jokinen, E, Sabin, MA, Laitinen, T, Elovainio, M, Pulkki-Raback, L, Viikari, JSA, Raitakari, OT, Juonala, M
Increasing evidence supports the importance of socioeconomic factors in the development of atherosclerotic cardiovascular disease. However, the association of childhood socioeconomic status (SES) with arterial stiffness in adulthood has not been reported. Our aim was to determine whether higher childhood family-level SES is associated with lower arterial stiffness in adulthood. The analyses were performed using data gathered within the longitudinal Young Finns Study. The sample comprised 2566 participants who had data concerning family SES at ages 3 to 18 years in 1980 and arterial pulse wave velocity and carotid artery distensibility measured 21 or 27 years later in adulthood. Higher family SES in childhood was associated with lower arterial stiffness in adulthood; carotid artery distensibility being higher (β value ± SE, 0.029 ± 0.0089%/10 mm Hg; P = 0.001) and pulse wave velocity lower (β value ± SE, -0.062 ± 0.022 m/s; P = 0.006) among those with higher family SES in a multivariable analysis adjusted with age, sex, and conventional childhood cardiometabolic risk factors. The association remained significant after further adjustment for participant's SES in adulthood (β value ± SE, 0.026 ± 0.010%/10 mm Hg; P = 0.01 for carotid artery distensibility and β value ± SE, -0.048 ± 0.023 m/s; P = 0.04 for pulse wave velocity) but attenuated after adjustment for adulthood cardiometabolic risk factors (β value ± SE, 0.015 ± 0.008%/10 mm Hg; P = 0.08 for carotid artery distensibility and β value ± SE, -0.019 ± 0.02 m/s; P = 0.38 for pulse wave velocity). In conclusion, we observed an association between higher family SES in childhood and lower arterial stiffness in adulthood. Our findings suggest that special attention could be paid to children from low SES families to prevent cardiometabolic diseases primordially.

History

Publication title

Hypertension

Volume

70

Issue

4

Pagination

729-735

ISSN

0194-911X

Department/School

Menzies Institute for Medical Research

Publisher

Lippincott Williams & Wilkins

Place of publication

530 Walnut St, Philadelphia, USA, Pa, 19106-3621

Rights statement

© 2018 American Heart Association, Inc

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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