University of Tasmania

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Chromatographic performance of synthetic polycrystalline diamond as a stationary phase in normal phase high performance liquid chromatography

journal contribution
posted on 2023-05-18, 09:40 authored by Peristyy, A, Brett PaullBrett Paull, Nesterenko, PN
The chromatographic properties of high pressure high temperature synthesised diamond (HPHT) are investigated in normal phase mode of high performance liquid chromatography. Purified nonporous irregular shape particles of average particles size 1.2 μm and specific surface area 5.1 m2 g−1 were used for packing 100 × 4.6 mm ID or 50 × 4.6 mm ID stainless steel columns. The retention behaviour of several classes of compounds including alkyl benzenes, polyaromatic hydrocarbons (PAH), alkylphenylketones, phenols, aromatic acids and bases were studied using n-hexane-2-propanol mixtures as mobile phase. The results are compared with those observed for microdispersed sintered detonation nanodiamond (MSDN) and porous graphitic carbon (PGC). HPHT diamond revealed distinctive separation selectivity, which is orthogonal to that observed for porous graphitic carbon; while selectivities of HPHT diamond and microdispersed sintered detonation nanodiamonds are similar. Owing to non-porous particle nature, columns packed with high pressure high temperature diamond exhibited excellent mass transfer and produce separations with maximum column efficiency of 128,200 theoretical plates per meter.


Australian Research Council


Publication title

Journal of Chromatography A








School of Natural Sciences


Elsevier Science Bv

Place of publication

Po Box 211, Amsterdam, Netherlands, 1000 Ae

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Copyright 2015 Elsevier B.V.

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Socio-economic Objectives

Expanding knowledge in the chemical sciences