The sequencing of the human genome has seen the emergence of the direct-to-consumer (DTC) genetic-testing market, which allows individuals to obtain information about their genetic profile and its many health and lifestyle implications. Genetics play an important role in the development of many eye diseases, however, little information is available describing the influence of the DTC industry in ophthalmology. In this review, we examined DTC companies providing genetic test products for eye disease. Of all eye conditions, the majority of DTC companies provided susceptibility testing or risk assessment for age-related macular degeneration (AMD). For the 15 companies noted to offer products, we found considerable variation in the cost, scope and clarity of informational content of DTC genetic testing for ophthalmic conditions. The clinical utility of these tests remains in question, and the American Academy of Ophthalmology recommendations against routine testing for many conditions probably still apply.
History
Publication title
Clinical and Experimental Ophthalmology
Volume
43
Issue
6
Pagination
578-590
ISSN
1442-6404
Department/School
Tasmanian School of Medicine
Publisher
Blackwell Publishing Asia
Place of publication
54 University St, P O Box 378, Carlton, Australia, Victoria, 3053
Rights statement
Copyright 2015 Royal Australian and New Zealand College of Ophthalmologists