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134903 - Dietary patterns and &%23946;-amyloid deposition in aging Australian women.pdf (750.72 kB)

Dietary patterns and β-amyloid deposition in aging Australian women

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journal contribution
posted on 2023-05-20, 07:04 authored by Eddy RoccatiEddy Roccati, Clifton, P, Goodwill, AM, Dennerstein, L, Campbell, S, Szoeke, C
Introduction: Evidence indicates that associations between diet and Alzheimer's disease may occur through biomarker pathways such as amyloid-β (Aβ); however, few studies have investigated dietary/Aβ relationships, and no study has investigated this relationship in women.

Methods: Dietary patterns were extrapolated for 115 participants from the Women's Health Aging Project. Aβ deposition was measured via in vivo F-18 florbetaben positron emission tomography scanning.

Results: Participants were, on average, aged 70 years (±2.63 SD), had 13 years of education (±3.57 SD), a BMI of 28 kg/m2 (±5.46 SD), and a daily energy intake of 5161 kJ (±1679.03 SD). Four dietary patterns were identified: high fat, Mediterranean, junk food, and low fat. Adherence to the junk food diet was a significant predictor of Aβ deposition (β = .10, P = .03).

Discussion: This study highlights the potential of diet to influence neurodegenerative disease and as a potential modifiable lifestyle risk factor for Alzheimer's disease.


Publication title

Alzheimer's & Dementia








Menzies Institute for Medical Research


Elsevier Inc.

Place of publication

United States

Rights statement

Copyright 2018 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer’s Association. This is an open access article under the CC BY-NC-ND license (

Repository Status

  • Open

Socio-economic Objectives

Clinical health not elsewhere classified; Nutrition