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Differential relationships between anthropometry measures and cardiovascular risk factors in boys and girls

journal contribution
posted on 2023-05-18, 19:35 authored by Huang, RC, de Klerk, N, Mori, TA, Newnham, JP, Stanley, FJ, Landau, LI, Wendy OddyWendy Oddy, Hands, B, Beilin, LJ
OBJECTIVES: The aim of the study was to compare commonly used anthropometry for cardiovascular risk factors in 14-year-olds.

METHODS: A total of 1 149 children of an Australian pregnancy (Raine) cohort with recruitment 1989-1991 were assessed for anthropometry and fasting lipids, insulin, and blood pressure.

RESULTS: There were significant distinctions in the associations between anthropometry and groups of cardiovascular risk factors. These distinctions differed by gender. Insulin resistance, triglycerides, C-reactive protein levels, low density lipoprotein (LDH)/high density lipoprotein (HDL) and total/HDL cholesterol ratios had the strongest association with waist, waist/height ratio and body mass index. By contrast, in boys, height was the strongest independent predictor (in a negative direction) of total and LDL-cholesterol. Blood pressure and uric acid was most strongly correlated with body weight and height (heavier and taller boys). Taller male adolescents had highest blood pressures and lowest cholesterol levels.

CONCLUSIONS: No single adolescent anthropometric measure best predicted all cardiovascular risk factors. Each measure showed distinct relationships with specific groups of risk factors. Contrasting associations may reflect different pathogenesis by which gender, puberty, and adiposity affect metabolic risk. No single anthropometric measurement in childhood would appear to be superior or sufficient when investigating the developmental origins of cardiovascular health and related metabolic disease.

History

Publication title

International Journal of Pediatric Obesity

Volume

6

Pagination

e271-282

ISSN

1747-7166

Department/School

Menzies Institute for Medical Research

Publisher

Wiley-Blackwell Publishing Ltd.

Place of publication

United Kingdom

Repository Status

  • Restricted

Socio-economic Objectives

Nutrition

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    University Of Tasmania

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