Ecological and evolutionary consequences of anticancer adaptations
journal contributionposted on 2023-05-21, 07:59 authored by Boutry, J, Dujon, AM, Gerard, AL, Tissot, S, Macdonald, N, Schultz, A, Biro, PA, Beckmann, C, Rodrigo Hamede RossRodrigo Hamede Ross, David HamiltonDavid Hamilton, Giraudeau, M, Ujvari, B, Thomas, F
Cellular cheating leading to cancers exists in all branches of multicellular life, favoring the evolution of adaptations to avoid or suppress malignant progression, and/or to alleviate its fitness consequences. Ecologists have until recently largely neglected the importance of cancer cells for animal ecology, presumably because they did not consider either the potential ecological or evolutionary consequences of anticancer adaptations. Here, we review the diverse ways in which the evolution of anticancer adaptations has significantly constrained several aspects of the evolutionary ecology of multicellular organisms at the cell, individual, population, species, and ecosystem levels and suggest some avenues for future research.
Department/SchoolSchool of Natural Sciences
Place of publicationUnited States
Rights statementThis is an open access article under the CC BY-NC-ND license http://creativecommons.org/licenses/by-nc-nd/4.0/).