150230 - Ecological and evolutionary consequences of anticancer adaptations.pdf (1.24 MB)
Download fileEcological and evolutionary consequences of anticancer adaptations
journal contribution
posted on 2023-05-21, 07:59 authored by Boutry, J, Dujon, AM, Gerard, AL, Tissot, S, Macdonald, N, Schultz, A, Biro, PA, Beckmann, C, Rodrigo Hamede RossRodrigo Hamede Ross, David HamiltonDavid Hamilton, Giraudeau, M, Ujvari, B, Thomas, FCellular cheating leading to cancers exists in all branches of multicellular life, favoring the evolution of adaptations to avoid or suppress malignant progression, and/or to alleviate its fitness consequences. Ecologists have until recently largely neglected the importance of cancer cells for animal ecology, presumably because they did not consider either the potential ecological or evolutionary consequences of anticancer adaptations. Here, we review the diverse ways in which the evolution of anticancer adaptations has significantly constrained several aspects of the evolutionary ecology of multicellular organisms at the cell, individual, population, species, and ecosystem levels and suggest some avenues for future research.
History
Publication title
iScienceVolume
23Issue
11Article number
101716Number
101716Pagination
1-13ISSN
2589-0042Department/School
School of Natural SciencesPublisher
Cell PressPlace of publication
United StatesRights statement
This is an open access article under the CC BY-NC-ND license http://creativecommons.org/licenses/by-nc-nd/4.0/).Repository Status
- Open