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Emerging therapeutic potential of the iridoid molecule, asperuloside: A snapshot of its underlying molecular mechanisms
journal contributionposted on 2023-05-20, 09:22 authored by Chan, Y, Ng, SW, Xin Tan, JZ, Gupta, G, Tambuwala, MM, Bakshi, HA, Dureja, H, Dua, K, Ishaq, M, Vanni CarusoVanni Caruso, Chellappan, DK
Over the years, the attention of researchers in the field of modern drug discovery and development has become further intense on the identification of active compounds from plant sources and traditional remedies, as they exhibit higher therapeutic efficacies and improved toxicological profiles. Among the large diversity of plant extracts that have been discovered and explored for their potential therapeutic benefits, asperuloside, an iridoid glycoside, has been proven to provide promising effects as a therapeutic agent for several diseases. Although, this potent substance exists in several genera, it is primarily found in plants belonging to the genus Eucommia. Recent decades have seen a surge in the research on Asperuloside, making it one of the most studied natural products in the field of medicine and pharmacology. In this review, we have attempted to study the various reported mechanisms of asperuloside that form the basis of its wide spectrum of pharmacological activities.
Publication titleChemico-Biological Interactions
Department/SchoolSchool of Pharmacy and Pharmacology
Place of publicationIreland
Rights statementCopyright 2019 Elsevier Ltd.