University Of Tasmania

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Enantioselective Toxicity and Carcinogenesis

journal contribution
posted on 2023-05-17, 00:16 authored by Ali, I, Aboul-Enein, HY, Ghanem, A
In a non-chiral environment, the enantiomers of a racemate possess the same physico-chemical properties but in the biological systems they possess different activities. One of the enantiomers may be more toxic or carcinogenic, and, therefore, the present data available on the toxicity and carcinogenesis of the racemic mixtures of these chiral pollutants are not reliable and need modification in terms of the enantioselective toxicity and carcinogenesis. It is essential to explore the enantioselective toxicity and carcinogenesis due to the different enantiomers of the chiral pollutants. The knowledge of the stereoselective metabolisms of the chiral pollutants may be useful for the treatment of cancer and other diseases. The enantioselective toxicity and carcinogenesis due to the chiral pesticides, pollutants and some drugs have been discussed in this review article.


Publication title

Current Pharmaceutical Analysis






School of Natural Sciences


Bentham Science Publishers

Place of publication

United Kingdom

Rights statement

Copyright © 2005 Bentham Science Publishers Ltd.

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the chemical sciences