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Factors associated with medication regimen complexity in residents of long-term care facilities

journal contribution
posted on 2023-05-18, 17:02 authored by Herson, M, Bell, JS, Tan, ECK, Emery, T, Robson, L, Barbara Wimmer
Background: Polypharmacy and multimorbidity are highly prevalent in long-term care facilities (LTCFs). However, no previous research has investigated factors associated with medication regimen complexity in older residents living in LTCFs.

Objective: To investigate factors associated with medication regimen complexity in LTCFs.

Methods: This was a cross-sectional study across six LTCFs in South Australia. Medication, clinical anddiagnostic data were extracted from each residents medication and medical record. Residents’ medication regimen complexity was quantified using the validated 65-item Medication Regimen Complexity Index (MRCI). Multinomial logistic regression analyses were used to compute unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for variables associated with high regimen complexity.

Results: There were a total of 383 participants in the study. The mean age of the participants was 87.5 (standard deviation [SD]: 6.2) years. The median MRCI was 43.5 (range: 4–113). The median number of regular and as-needed medications was 13.0 (range: 1–30). Chronic pulmonary disease (OR: 5.10, 95% CI: 2.21–11.8), diabetes (OR: 3.22, 95% CI: 1.51–6.86) and congestive heart failure (OR: 3.13, 95% CI: 1.10–8.85) were associated with high regimen complexity. Independence in activities of daily living (ADLs) (OR: 0.72, 95% CI: 0.62–0.84) and diagnosed dementia (OR: 0.34, 95% CI: 0.17–0.67) were inversely associated with high regimen complexity.

Conclusion: LTCF residents are at-risk of high medication regimen complexity. Diabetes, congestive heart failure and chronic pulmonary diseases were associated with high regimen complexity, whereas dementia was inversely associated with high regimen complexity.

History

Publication title

European Geriatric Medicine

Volume

6

Pagination

561-564

ISSN

1878-7649

Department/School

School of Pharmacy and Pharmacology

Publisher

Elsevier Ltd

Place of publication

United Kingdom

Rights statement

Copyright? 2015 Elsevier Masson SAS and European Union Geriatric Medicine Society. All rights reserved.

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the health sciences

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