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Follow-Up of Pulmonary Hypertension With Echocardiography
journal contributionposted on 2023-05-18, 21:59 authored by Wright, LM, Dwyer, N, Celermajer, D, Kritharides, L, Thomas MarwickThomas Marwick
Individual patient response to effective therapies for pulmonary hypertension (PAH) is variable and difficult to quantify. Consequently, management decisions regarding initiation and continuation of therapy are highly dependent on the results of investigations. Registry data show that changes in cardiac index, mean right atrial pressure, and mean pulmonary artery pressure have the greatest influence on survival. It is recognized that pulmonary artery pressure (PASP) responses to PAH-specific drugs are heterogeneous. However, follow-up testing is strongly focused on assessing changes in PASP and functional status (6-min walk). The goals of therapy, which should be highlighted in follow-up imaging, include not only reduction of PASP, decrease in pulmonary vascular resistance, and improvements in right ventricular function, cardiac output, and tricuspid regurgitation. This paper reviews the echocardiographic follow-up of pulmonary hypertension, and especially focuses on right ventricular functionâ€”a major determinant of outcome, for which reliable echocardiographic assessment has become more feasible.
Publication titleJACC: Cardiovascular Imaging
Department/SchoolMenzies Institute for Medical Research
Place of publicationUnited States
Rights statementCopyright 2016 by the American College of Cardiology Foundation