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GORK channel: a master switch of plant metabolism?
journal contributionposted on 2023-05-20, 15:14 authored by Adem, GD, Chen, G, Svetlana ShabalaSvetlana Shabala, Chen, Z-H, Sergey ShabalaSergey Shabala
Potassium regulates a plethora of metabolic and developmental response in plants, and upon exposure to biotic and abiotic stresses a substantial K+ loss occurs from plant cells. The outward-rectifying potassium efflux GORK channels are central to this stress-induced K+ loss from the cytosol. In the mammalian systems, signaling molecules such as gamma-aminobutyric acid, G-proteins, ATP, inositol, and protein phosphatases were shown to operate as ligands controlling many K+ efflux channels. Here we present the evidence that the same molecules may also regulate GORK channels in plants. This mechanism enables operation of the GORK channels as a master switch of the cell metabolism, thus adjusting intracellular K+ homeostasis to altered environmental conditions, to maximize plant adaptive potential.
Publication titleTrends in Plant Science
Department/SchoolTasmanian Institute of Agriculture (TIA)
PublisherElsevier Science London
Place of publication84 Theobalds Rd, London, England, Wc1X 8Rr
Rights statement© 2019 Elsevier Ltd. All rights reserved.