Genetic and epigenetic variation in vulvar cancer: Current research and future clinical practice
journal contributionposted on 2023-05-18, 03:07 authored by Rebekah McWhirterRebekah McWhirter, James MarthickJames Marthick, Boyle, JA, Joanne DickinsonJoanne Dickinson
Vulvar cancer is a relatively rare gynaecological malignancy, the treatment of which is associated with significant patient morbidity. With reports that the incidence of vulvar cancer is increasing, there is a rising need for improved preventive, diagnostic and therapeutic tools. Recent advances within genetics and epigenetics present possible approaches for addressing this need, by contributing to the clarification of the aetiology of this disease, identifying screening and drug targets and introducing the potential for personalised treatments. This paper reviews the genetic and epigenetic research undertaken to date within vulvar cancer, evaluates its potential for clinical application and identifies directions for future research. © 2014 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.
Publication titleThe Australian and New Zealand Journal of Obstetrics and Gynaecology
Department/SchoolMenzies Institute for Medical Research
PublisherWiley-Blackwell Publishing Asia
Place of publicationAustralia
Rights statementCopyright 2014 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists