Gold-catalyzed and N-iodosuccinimide-mediated cyclization of γ-substituted allenamides
journal contribution
posted on 2023-05-17, 07:52authored byHyland, CJT, Hegedus, LS
Chiral gamma-substituted allenamides have been shown to undergo efficient gold-catalyzed and N-iodosuccinimide-mediated cyclization to highly functionalized dihydrofurans. These reactions proceed rapidly and without loss of stereochemistry.