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Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanism
journal contribution
posted on 2023-05-19, 14:43 authored by Ghari, H, Li, Y, Roohzadeh, R, Caramenti, P, Waser, J, Alireza AriafardAlireza AriafardGold-catalyzed domino processes constitute a useful alternative to C–H functionalization for the synthesis of functionalized (hetero)arenes. Herein, we report computational studies on the gold-catalyzed cyclization alkynylation of keto-allenes with ethynylbenziodoxole (EBX) reagents, which identified a gold(I) picolinate complex as the active catalyst, giving the first mechanistic insights into this transformation.
History
Publication title
Dalton TransactionsVolume
46Issue
36Pagination
12257-12262ISSN
1477-9226Department/School
School of Natural SciencesPublisher
Royal Soc ChemistryPlace of publication
Thomas Graham House, Science Park, Milton Rd, Cambridge, England, Cambs, Cb4 0WfRights statement
Copyright 2017 The Royal Society of ChemistryRepository Status
- Restricted