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Growth factors and trefoil peptides in gastrointestinal health and disease
journal contributionposted on 2023-05-17, 08:07 authored by Playford, RJ, Ghosh, S, Mahmood, A
Peptide growth factors are a fascinating group of molecules with diverse effects. Recent developments have allowed us to gain a much greater insight into their pathophysiological functions. In addition, the development of recombinant peptide technology, monoclonal antibody production and both artificial small molecule receptor agonists and inhibitors now allows us to use these factors for the treatment of multiple conditions including gastrointestinal malignancy (particularly colonic carcinoma), short bowel syndrome (where factors such as growth hormone, epidermal growth factor and glucagons-like peptide 2 show particular promise), and inflammatory bowel disease. Â© 2004 Elsevier Ltd. All rights reserved.
Publication titleCurrent Opinion in Pharmacology
Department/SchoolCollege Office - College of Health and Medicine
PublisherElsevier Sci Ltd
Place of publicationThe Boulevard, Langford Lane, Kidlington, Oxford, England, Oxon, Ox5 1Gb