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Influence of comorbid depression on fear in posttraumatic stress disorder: An fMRI study
journal contribution
posted on 2023-05-17, 07:20 authored by Kemp, AH, Kim FelminghamKim Felmingham, Das, P, Hughes, G, Peduto, A, Bryant, RA, Williams, LMPosttraumatic Stress Disorder (PTSD) is thought to involve a dysregulation of medial prefrontal–amygdala activity in response to fear. PTSD studies, however, have been confounded by comorbid depression, which shows similar dysregulation. Amygdala and medial prefrontal activity was reduced in PTSD-depression compared to PTSD-alone samples, highlighting the need to account for comorbidity.
History
Publication title
Psychiatry Research: Neuroimaging SectionVolume
155Pagination
265-269ISSN
0925-4927Department/School
School of Psychological SciencesPublisher
Elsevier Sci Ireland LtdPlace of publication
Customer Relations Manager, Bay 15, Shannon Industrial Estate Co, Clare, IrelandRights statement
Copyright © 2007 Elsevier Ireland Ltd. The definitive version is available at http://www.sciencedirect.comRepository Status
- Restricted
