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Inherited pyruvate kinase deficiency and normal haematological values in Australian Basenji dogs
journal contribution
posted on 2023-05-17, 06:13 authored by Hogg, GG, Brian HortonBrian Horton, Brown, HSUMMARY We have carried out a survey to determine the prevalence of carriers of pyruvate kinase deficiency haemolytic anaemia in Basenjis in Victoria. Of 186 dogs tested, 20 were found to be carriers for pyruvate kinase deficiency, a prevalence similar to that reported overseas. Of the 20 carriers found, 17 were born in Australia and were traced directly to 1 of the 3 imported carriers. Despite the relatively high frequency of carriers, no mating of 2 carriers has yet been detected and no dogs with haemolytic anaemia have been observed. The inheritance of the pyruvate kinase deficiency has been traced through up to 5 generations of dogs in Australia and is consistent with coâ€dominance for pyruvate kinase activity and with an autosomal recessive gene for haemolytic anemia. Copyright © 1978, Wiley Blackwell. All rights reserved
History
Publication title
Australian Veterinary JournalVolume
54Pagination
367-370ISSN
0005-0423Department/School
Tasmanian Institute of Agriculture (TIA)Publisher
Australian Veterinary AssnPlace of publication
272 Brunswick Rd Brunswick, Melbourne, Australia, Vic, 3056Repository Status
- Restricted