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Ion chromatography on-chip
journal contribution
posted on 2023-05-16, 12:59 authored by Murrihy, JP, Michael BreadmoreMichael Breadmore, Tan, A, McEnery, M, Alderman, J, O'Mathuna, C, O'Neill, AP, O'Brien, P, Advoldvic, N, Paul HaddadPaul Haddad, Glennon, JDOn-chip separation of inorganic anions by ion-exchange chromatography was realized. Micro separation channels were fabricated on a silicon wafer and sealed with a Pyrex cover plate using standard photolithography, wet and dry chemical etching, and anodic bonding techniques. Quaternary ammonium latex particles were employed for the first time to coat the separation channels on-chip. Owing to the narrow depths of the channels on the chip, 0.5–10 μm, there were more interactions of the analytes with the stationary phase on the chip than in a 50-μm I.D. capillary. With off-chip injection (20 nl) and UV detection, NO2−, NO3−, I−, and thiourea were separated using 1 mM KCl as the eluent. The linear ranges for NO2− and NO3− are from 5 to 1000 μM with the detection limits of 0.5 μM.
History
Publication title
Journal of Chromatography AVolume
924Issue
1-2Pagination
233-238ISSN
0021-9673Department/School
School of Natural SciencesPublisher
Elsevier Science BVPlace of publication
AmsterdamRights statement
The definitive version is available at http://www.sciencedirect.comRepository Status
- Restricted