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Management of cow's milk protein allergy in infants and young children: An expert panel perspective

journal contribution
posted on 2023-05-17, 02:00 authored by Allen, KJ, Davidson, GP, Day, AS, Hill, DJ, Kemp, AS, Peake, JE, Prescott, SL, Shugg, AW, Sinn, JKH, Heine, RG
Cow’s milk protein allergy is a condition commonly managed by general practitioners and paediatricians. The diagnosis is usually made in the first 12 months of life. Management of immediate allergic reactions and anaphylaxis includes the prevention of accidental food ingestion and provision of an adrenaline autoinjector, if appropriate. By contrast, the clinical course of delayed food-allergic manifestations is characterised by chronicity, and is often associated with nutritional or behavioural sequelae. Correct diagnosis of these non-IgE-mediated conditions may be delayed due to a lack of reliable diagnostic markers. This review aims to guide clinicians in the: (i) diagnostic evaluation (skin prick testing or measurement of food-specific serum IgE levels; indications for diagnostic challenges for suspected IgE- and non-IgE-mediated food allergy), (ii) dietary treatment, (iii) assessment of response to treatment, (iv) differential diagnosis and further diagnostic work-up in non-responders, (v) follow-up assessment of tolerance development and (vi) recommendations for further referral.

History

Publication title

Journal of Paediatrics and Child Health

Volume

45

Issue

9

Pagination

481-486

ISSN

1034-4810

Department/School

Tasmanian School of Medicine

Publisher

Wiley-Blackwell

Place of publication

Melbourne, Australia

Rights statement

The definitive published version is available online at: http://www.interscience.wiley.com

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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