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Mode of Delivery and Childhood Blood Pressure

journal contribution
posted on 2023-05-16, 12:06 authored by Morley, R, Kennedy, K, Lucas, A, Christopher BlizzardChristopher Blizzard, Terry DwyerTerry Dwyer
A number of studies have shown that children born by cesarean section have lower blood pressure during the neonatal period. The aim of this study was to investigate whether mode of delivery influenced childhood blood pressure: at age 7.5 to 8 y in a cohort of 756 children born preterm, at 7 to 9 y in a pilot study of 166 children born at term in the United Kingdom, and in a cohort of 650 Tasmanian children born at term. In the preterm cohort, systolic blood pressure was significantly lower in children born by cesarean section rather than delivered vaginally (99.3 ± 10.0versus101.4 ± 9.4 mm Hg; 95% confidence interval, 0.69 to 3.46p= 0.003), with a significant trend to having a higher pressure in those born by breechversusforcepsversusspontaneous vaginal deliveryversuscesarean section. These findings were not replicated in the term cohorts. This raises the hypothesis that there is a sensitive period for programming later blood pressure by factors associated with mode of delivery and that this period does not extend to full-term.© International Pediatrics Research Foundation, Inc. 2000. All Rights Reserved.

History

Publication title

Pediatric Research

Volume

47

Issue

4

Pagination

463-467

ISSN

0031-3998

Department/School

Menzies Institute for Medical Research

Publisher

International Pediatric Research Foundation

Place of publication

USA

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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