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Multi‑omics reveals mechanisms of resistance to potato root infection by Spongospora subterranea

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posted on 2023-05-21, 14:38 authored by Sadegh Balotf, Richard WilsonRichard Wilson, David NicholsDavid Nichols, Robert TeggRobert Tegg, Calum WilsonCalum Wilson
The pathogen Spongospora subterranea infects potato roots and developing tubers resulting in tuber yield and quality losses. Currently, there are no fully effective treatments for disease control. Host resistance is an important tool in disease management and understanding the molecular mechanisms of defence responses in roots of potato plants is required for the breeding of novel resistant cultivars. Here, we integrated transcriptomic and proteomic datasets to uncover these mechanisms underlying S. subterranea resistance in potato roots. This multi-omics approach identified upregulation of glutathione metabolism at the levels of RNA and protein in the resistant cultivar but not in the susceptible cultivar. Upregulation of the lignin metabolic process, which is an important component of plant defence, was also specific to the resistant cultivar at the transcriptome level. In addition, the inositol phosphate pathway was upregulated in the susceptible cultivar but downregulated in the resistant cultivar in response to S. subterranea infection. We provide large-scale multi-omics data of Spongospora-potato interaction and suggest an important role of glutathione metabolism in disease resistance.

Funding

Australian Research Council

History

Publication title

Scientific Reports

Volume

12

Article number

10804

Number

10804

Pagination

1-13

ISSN

2045-2322

Department/School

Tasmanian Institute of Agriculture (TIA)

Publisher

Nature Publishing Group

Place of publication

United Kingdom

Rights statement

© 2022. The Authors. This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Repository Status

  • Open

Socio-economic Objectives

Field grown vegetable crops

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