University Of Tasmania
151442 - Natural products isolation studies of native Australian fern species.pdf (999.33 kB)
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Natural products isolation studies of native Australian fern species

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journal contribution
posted on 2023-05-21, 10:06 authored by Thinley GyeltshenThinley Gyeltshen, Jason SmithJason Smith, Alexander BissemberAlexander Bissember
Natural products isolation studies of 16 native Australian fern species have been undertaken, facilitated by pressurised hot water extraction (PHWE). Fourteen of these fern species have not been the subject of natural products isolation research previously. In total, 14 different compounds were isolated from 12 of these 16 different fern species. This included γ- and δ-lactones; flavonoid glycosides, a dihydrobenzofuran neolignan, in addition to hydroxycinnamate/caffeic acid esters. More specifically, the lactones 5,6-dihydro-5-hydroxy-6-methyl-2H-pyran-2-one, 5-(1-hydroxyethyl)-2(5H)-furanone and osmundalin were obtained from Todea barbara, while a dihydrobenzofuran neolignan, (−)-trans-blechnic acid were found in Austroblechnum penna-marina subsp. alpina, and the shikimate ester 5-O-caffeoylshikimic acid was isolated from Parablechnum wattsii. In addition, flavonoids and their glycoside derivatives, kaempferol 3-O-glucopyranoside, 4β-carboxymethyl-(−)-epicatechin, (2R)-eriodictyol-7-O-β-d-glucopyranoside, naringin, quercitrin, quercetin 3-O-(6″-acetyl)-β-d-glucopyranoside, rutin, and tiliroside were isolated from seven other fern species.


Australian Research Council


Publication title

Australian Journal of Chemistry










School of Natural Sciences


CSIRO Publishing

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150 Oxford St, Po Box 1139, Collingwood, Australia, Victoria, 3066

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© 2022 The Author(s). Published by CSIRO Publishing. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License ( which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed.

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Socio-economic Objectives

Expanding knowledge in the chemical sciences