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Oxygen as a therapy for reducing nicotine withdrawal symptoms

journal contribution
posted on 2023-05-16, 17:33 authored by Granger, R
Nicotine addiction leads to withdrawal symptoms in many persons who quit smoking. In addition to craving, the most commonly experienced symptoms are: depression; difficulty sleeping; irritability, frustration, or anger; anxiety; difficulty concentrating; restlessness; decreased heart rate; and increased appetite or weight gain. The severity of withdrawal symptoms are variable, and often lead to relapse. By altering the course of withdrawal symptoms it is possible to improve the chances of the quit attempt and reduce the risk of relapse. There is strong evidence that dopamine is the primary neurotransmitter in the reward pathway in addiction. The use of nicotine replacement therapies and Zyban (sustained release bupropion hydrochloride), both of which are suspected of exploiting dopamine's role in addiction, enhance the likelihood of long-term smoking cessation. Anecdotal reports of oxygen's capacity to reduce both the desire for nicotine and withdrawal symptoms suggest that this may be a therapeutic possibility for those who do not experience success with more traditional cessation approaches. Oxygen may have a favorable effect on nicotine withdrawal, as it appears to alter the balance of central neurotransmitters such as dopamine. © 2005 Elsevier Ltd. All rights reserved.

History

Publication title

Medical Hypotheses

Volume

65

Issue

6

Pagination

1161-1164

ISSN

0306-9877

Department/School

Menzies Institute for Medical Research

Publisher

Churchill Livingstone

Place of publication

Edinburgh, Scotland

Repository Status

  • Restricted

Socio-economic Objectives

Behaviour and health

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    University Of Tasmania

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