University Of Tasmania
Patterns_of_peripheral_steroid_metabolism_vary_with_sex,_season,_and_tissue_type_in_blotched_blue-tongued_lizards_(Tiliqua_nigrolutea).pdf (472.82 kB)
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Patterns of peripheral steroid metabolism vary with sex, season, and tissue type in blotched blue-tongued lizards (Tiliqua nigrolutea)

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journal contribution
posted on 2023-05-16, 16:09 authored by Ashley EdwardsAshley Edwards, Susan JonesSusan Jones, Noel DaviesNoel Davies
We examined sexual and seasonal variation in the ability of reproductively relevant tissues (liver, skin, adrenal gland, cloaca, kidney, renal sexual segment, epididymis, oviduct, muscle, testis, and ovary) to metabolise a primary steroid [testosterone (T) or estradiol (E2)] in the scincid lizard, Tiliqua nigrolutea. We observed considerable variation between sexes and across seasons in the patterns of conjugation and derivatisation of the primary steroids by these tissues. All tissues demonstrated the ability to conjugate the relevant primary steroid. Other general trends included increased conjugation by all tissues of gestating females, reduced metabolism of E2 by female tissues during late vitellogenesis, and reduced metabolism of T by males during early spermatogenesis. 5α-Dihydrotestosterone was the most commonly detected derivative in males, and production varied with season and tissue type. We suggest that seasonal variation in the ability of reproductively relevant tissues may be important in the physiological regulation of reproduction in this species. © 2004 Elsevier Inc. All rights reserved.


Publication title

General and Comparative Endocrinology








School of Natural Sciences


Academic Press Inc

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Expanding knowledge in the environmental sciences