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84379 - Physical activity and depression symptom profiles - Final author version.pdf (1.11 MB)

Physical activity and depression symptom profiles in young men and women with major depression

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posted on 2023-05-17, 17:26 authored by Charlotte McKercher, Patton, GC, Schmidt, MD, Alison VennAlison Venn, Dwyer, T, Kristy Sanderson
Objective This study explored whether young adults with major depression who are physically active differ in their depression symptom profile from those physically inactive. Methods Analyses included data from 950 (47.6%) men and 1045 women (mean [standard deviation] age = 31.5 [2.6] years) participating in a national study. Participants reported leisure physical activity (International Physical Activity Questionnaire) and ambulatory activity (pedometer steps per day). Diagnosis and symptoms of major depression were assessed using the Composite International Diagnostic Interview. Results Prevalence of major depression was 5.5% (n = 52) for men and 11.6% (n = 121) for women. Interactions between physical activity and sex were observed for depressed mood, appetite changes, vacillating thoughts, and suicidality (all, p < .050). Among those with major depression, physically active men were significantly less likely to endorse the presence of insomnia (prevalence ratio [PR] = 0.78, 95% confidence interval [CI] = 0.63-0.96), fatigue (PR = 0.82, 95% CI = 0.69-0.99), and suicidality (PR = 0.69, 95% CI = 0.49-0.96) compared with inactive men. Physically active women were significantly less likely to endorse hypersomnia (PR = 0.50, 95% CI = 0.27-0.95), excessive/irrational guilt (PR = 0.76, 95% CI = 0.59-0.97), vacillating thoughts (PR = 0.74, 95% CI = 0.58-0.95), and suicidality (PR = 0.43, 95% CI = 0.20-0.89) compared with inactive women. Associations were adjusted for age, physical health, educational attainment, depression severity, and other depressive symptoms. Conclusions Among adults with major depression, those physically active seem to differ in their depression symptom profile from those physically inactive.


Publication title

Psychosomatic Medicine










Menzies Institute for Medical Research


Lippincott Williams & Wilkins

Place of publication

530 Walnut St, Philadelphia, USA, Pa, 19106-3621

Rights statement

Copyright 2013 by the American Psychosomatic Society

Repository Status

  • Open

Socio-economic Objectives

Mental health

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