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Polygodial: a viable natural product scaffold for the rapid synthesis of novel polycyclic pyrrole and pyrrolidine derivatives
journal contributionposted on 2023-05-19, 16:37 authored by Rihak, KJ, Alexander BissemberAlexander Bissember, Jason SmithJason Smith
The dialdehyde polygodial was utilised as a chiral scaffold for the unified synthesis of novel polycyclic pyrrole and pyrrolidine derivatives. Mechanistic insight into the reaction of primary amines with this dialdehyde was obtained. In addition, one of these polycyclic pyrroles was transformed further to prepare novel pentacyclic frameworks.
Department/SchoolSchool of Natural Sciences
PublisherPergamon-Elsevier Science Ltd
Place of publicationThe Boulevard, Langford Lane, Kidlington, Oxford, England, Ox5 1Gb
Rights statementCopyright 2017 Elsevier Ltd.