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Porous layer open tubular columns in capillary liquid chromatography
journal contributionposted on 2023-05-18, 02:33 authored by Collins, DA, Nesterenko, EP, Brett PaullBrett Paull
This review covers the latest developments and applications of porous layer open tubular columns in capillary liquid chromatography. Here, the authors provide a concise background on the fundamentals of porous layer open tubular columns, their fabrication and application. Over the past two decades, growing interest in the areas of proteomics and hyphenated LC-MS techniques have played a large part in the development of porous layer structures within capillary formats due to their high permeability, excellent efficiency and exceptional peak capacity. This review gives a brief overview of open tubular columns in general, however, it focuses predominantly on the applications of covalently bonded porous layer open tubular columns in liquid chromatography. Open tubular columns containing non-bonded or electrostatically attached layers will not be discussed in detail.
Department/SchoolSchool of Natural Sciences
PublisherRoyal Soc Chemistry
Place of publicationThomas Graham House, Science Park, Milton Rd, Cambridge, England, Cambs, Cb4 0Wf
Rights statementCopyright 2014 The Royal Society of Chemistry