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Prevention of venous thromboembolism in hospitalized patients: analysis of reduced cost and improved clinical outcomes

journal contribution
posted on 2023-05-17, 20:02 authored by Jed Duff, Walker, K, Omari, A, Stratton, C
The impact of implementing a guideline on venous thromboembolism (VTE) prophylaxis was evaluated in a metropolitan private hospital with a before- and after-intervention study. This subsequent study aimed to identify if improved prophylaxis rates translated into cost savings and improved clinical outcomes. A conceptual decision-tree analytical model incorporating local treatment algorithms and clinical trial data was used to compare prophylaxis costs and clinical outcomes before and after the guideline implementation. The study analyzed data from 21,942 medical and surgical patients admitted to a 250-bed acute-care private hospital in Sydney, Australia. The modeled simulation estimated the incidence of symptomatic deep vein thrombosis (DVT) and pulmonary embolism (PE) as well as adverse events such as heparin-induced thrombocytopenia (HIT), post-thrombotic syndrome (PTS), major bleeding, and mortality. The costs of prophylaxis therapy and treating adverse events were also calculated. The improvement in prophylaxis rates following the implementation of the guideline was estimated to result in 13 fewer deaths, 84 fewer symptomatic DVTs, 19 fewer symptomatic PEs, and 512 fewer hospital-bed days. Improved adherence to evidence-based prophylaxis regimens was associated with overall cost savings of $245,439 over 12 months. We conclude that improved adherence to evidence-based guidelines for VTE prophylaxis is achievable and is likely to result in fewer deaths, fewer VTE events, and a significant overall cost saving. (J Vasc Nurs 2013;31:9-14)

History

Publication title

Journal of Vascular Nursing

Volume

31

Pagination

9-14

ISSN

1062-0303

Department/School

School of Nursing

Publisher

Mosby, Inc.

Place of publication

United States

Rights statement

Copyright 2013 by the Society for Vascular Nursing, Inc

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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