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Schizophrenic disorders. The development of immunological concepts and therapy in psychiatry

journal contribution
posted on 2023-05-17, 15:23 authored by Himmerich, H, Sorge, S, Kenneth KirkbyKenneth Kirkby, Steinberg, H
Immunological changes reported in patients with schizophrenia may play an aetiological role in these disorders. Further, immunomodulatory medications can influence the symptoms of psychiatric disorders. Antipsychotic agents such as clozapine may act therapeutically through the modulation of the immune system and also lead to side effects in that domain.Both the understanding and factual foundations of immunological concepts and immunological therapies of schizophrenic disorders have changed throughout the history of medicine. These are important considerations in psychiatry where diagnostic, nosological and therapeutic complexity is the norm. The article exemplarily presents publications of the psychiatrists such as Julius Wagner von Jauregg, Lewis Campbell Bruce and Friedrich Ostmann as well as neuropathologist Hermann Lehmann-Facius and haematologist William Dameshek.

History

Publication title

Nervenarzt

Volume

83

Pagination

7-15

ISSN

0028-2804

Department/School

Tasmanian School of Medicine

Publisher

Springer

Place of publication

Tiergartenstr 17, Heidelberg, 69121 Germany

Rights statement

Copyright 2012 Springer-Verlag

Repository Status

  • Restricted

Socio-economic Objectives

Mental health

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