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Studies on the synthesis of benzimidazo[2,1-a]isoquinolines
journal contributionposted on 2023-05-17, 13:54 authored by Deady, LW, Loria, PM, Thomas RodemannThomas Rodemann
The reaction of 1-(acetylimino)-3-methyl-1H-2-benzopyran-4-carbonitrile (I) with arom. ortho diamines provides entry to benzimidazo[2,1-a]isoquinolines, e.g., II, and related systems. Various conversions of the Me and cyano groups in the tetracycles to amide, aldehyde, and acid functions have been carried out, along with studies of electrophilic nitration.
Publication titleAustralian Journal of Chemistry: An International Journal for Chemical Science
PublisherC S I R O Publishing
Place of publication150 Oxford St, Po Box 1139, Collingwood, Australia, Victoria, 3066