The reaction of 1-(acetylimino)-3-methyl-1H-2-benzopyran-4-carbonitrile (I) with arom. ortho diamines provides entry to benzimidazo[2,1-a]isoquinolines, e.g., II, and related systems. Various conversions of the Me and cyano groups in the tetracycles to amide, aldehyde, and acid functions have been carried out, along with studies of electrophilic nitration.
History
Publication title
Australian Journal of Chemistry: An International Journal for Chemical Science
Volume
51
Issue
10
Pagination
941-945
ISSN
0004-9425
Publisher
C S I R O Publishing
Place of publication
150 Oxford St, Po Box 1139, Collingwood, Australia, Victoria, 3066