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The Antibody Response of Teleost Fish

journal contribution
posted on 2023-05-16, 13:22 authored by Morrison, RN, Barbara NowakBarbara Nowak
Intensively farmed fish are periodically subjected to stressful conditions, and this can lead to outbreaks of disease. Historically, disease in farmed fish was managed by the administration of chemotherapeutants. However, with the increase in antibiotic-resistant strains of bacteria, high cost of chemotherapy, short-term nature of protection, and public concerns about the use of chemicals, alternatives have been pursued. Although the first report of fish vaccination was published in the 1940s, it was not until the late 1970s that vaccination as a means of disease prevention became economic. Fish possess the ability to produce an antibody response to most antigens. However, a significant antibody response to an antigen does not always correlate with protection. Conversely, protection can be achieved without a significant antibody response. Here, we discuss the nature, expression, and distribution of fish immunoglobulin, including factors affecting the antibody response and uses of antibody in terms of immune status or exposure to pathogens. Copyright © 2002 by W.B. Saunders Company.


Publication title

Seminars in Avian and Exotic Pet Medicine








Institute for Marine and Antarctic Studies


WB Saunders Company

Place of publication

Philadelphia, Pennsylvania, USA

Repository Status

  • Restricted

Socio-economic Objectives

Fisheries - aquaculture not elsewhere classified

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