JCM-12-03791.pdf (901.83 kB)
The Complex Association between COPD and COVID-19
journal contributionposted on 2023-07-28, 05:29 authored by Nikhil T Awatade, Peter AB Wark, Andrew SL Chan, SM Abdullah Al Mamun, Nurul Yaqeen Mohd Esa, Kazuto Matsunaga, Chin Kook Rhee, Philip M Hansbro, Sukhwinder SohalSukhwinder Sohal, on behalf of the Asian Pacific Society of Respirology COPD Assembly
Chronic obstructive pulmonary disease (COPD) is significant cause of morbidity and mortality worldwide. There is mounting evidence suggesting that COPD patients are at increased risk of severe COVID-19 outcomes; however, it remains unclear whether they are more susceptible to acquiring SARS-CoV-2 infection. In this comprehensive review, we aim to provide an up-to-date perspective of the intricate relationship between COPD and COVID-19. We conducted a thorough review of the literature to examine the evidence regarding the susceptibility of COPD patients to COVID-19 infection and the severity of their disease outcomes. While most studies have found that pre-existing COPD is associated with worse COVID-19 outcomes, some have yielded conflicting results. We also discuss confounding factors such as cigarette smoking, inhaled corticosteroids, and socioeconomic and genetic factors that may influence this association. Furthermore, we review acute COVID-19 management, treatment, rehabilitation, and recovery in COPD patients and how public health measures impact their care. In conclusion, while the association between COPD and COVID-19 is complex and requires further investigation, this review highlights the need for careful management of COPD patients during the pandemic to minimize the risk of severe COVID-19 outcomes.
Publication titleJournal of Clinical Medicine
- Published online
Place of publicationSwitzerland
Event VenueImmune Health Program, Hunter Medical Research Institute and University of Newcastle, Newcastle 2305, Australia.
Rights statementCopyright 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/4.0/).
UN Sustainable Development Goals3 Good Health and Well Being