University Of Tasmania
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The influence of transcutaneous electrical nerve stimulation parameters on the level of pain perceived by participants with painful diabetic neuropathy: A crossover study

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journal contribution
posted on 2023-05-18, 21:50 authored by Upton, GA, Tinley, P, Al-Aubaidy, HA, Crawford, R

Aims: This pilot study aimed to investigate and compare the perceived pain relief effectiveness of two different modes of TENS in people with painful diabetic neuropathy (PDN).

Methods: A cross-over study was conducted at Charles Sturt University, Orange. Five participants with PDN were assessed with a McGill Pain Questionnaire before and after each of the two TENS treatments. Participants were randomly allocated to Traditional TENS (80 Hz, 200 ms) or Acupuncture-like TENS (2 Hz, 200 ms) and the treatments were applied daily for 30 minutes over ten days. Following a seven day washout period, the alternate mode of TENS was carried out using the same method. Wilcoxon Signed Rank tests were used to statistically analyse the results.

Results: All five participants reported personally meaningful pain relief during one or both of the TENS treatments. The Wilcoxon signed rank testing showed no statistical significance, p = 1, likely due to the small sample size. Acupuncture-like TENS had a large effect size (z = −1.625, r = 0.514), whilst Traditional TENS produced a medium effect size (z = −1.214, r = 0.384). No adverse effects were reported.

Conclusion: Acupuncture-like TENS may be more effective for PDN than traditional TENS. A larger scale replication of this pilot study is warranted.


Publication title

Diabetes & Metabolic Syndrome








Tasmanian School of Medicine


W.B. Saunders Co.

Place of publication

United States

Rights statement

Copyright 2016 Diabetes India

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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