University Of Tasmania

File(s) not publicly available

The toxicology and metabolism of chlorothalonil in fish. 1. Lethal levels for Salmo gairdneri, Galaxias maculatus, G. truttaceus and G. auratus and the fate of super(14)C-TCIN in S. gairdneri .

journal contribution
posted on 2023-05-25, 21:27 authored by Davies, PE, White, RWG
LC sub(50) values of chlorothalonil (TCIN) to Salmo gairdneri, Galaxias maculatus, G. truttaceus and G. auratus for 24, 48 and 96 h were determined using a flow-through apparatus. All values were lower than those previously reported for various fish species. The influence of decreased oxygen concentration and co-exposure of acephate on LC sub(50) values of TCIN to Salmo gairdneri was also investigated. Uptake of super(14)C-chlorothalonil in internal organs of Salmo gairdneri was measured during a 96 h exposure to 10 mu g/l in water. The primary site of accumulation was the bile. Levels in all other organs were in the mg/kg range and increased with time of exposure. Protein binding was observed in the liver. Release of polar labelled metabolites was constant with time over 96 h depuration, with 0.5% being TCIN. All organ levels dropped during this time. The possible route of TCIN metabolism is discussed.


Publication title

Aquatic Toxicology



Article number






Publication status

  • Published

Repository Status

  • Open

Usage metrics

    University Of Tasmania


    No categories selected