The toxicology and metabolism of chlorothalonil in fish. 2. Glutathione conjugates and protein binding.

The existence of mono- and diglutathione conjugates of chlorothalonil (TCIN) in the bile of Salmo gairdneri exposed to super(14)C-TCIN is confirmed. A detailed analysis of the structural nature of the conjugates is described, using model thioether analogues. The degree of protein binding of TCIN in liver cytosol and bile is reported.