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Trends in analytical separations of magnetic (nano)particles

journal contribution
posted on 2023-05-23, 00:02 authored by Alves, MN, Miro, M, Michael BreadmoreMichael Breadmore, Miroslav MackaMiroslav Macka
Magnetic particles (MPs) and magnetic nanoparticles (MNPs) are appealing candidates for biomedical and analytical applications due to their unique physical and chemical properties. Given that magnetic fields can be readily used to control the motion and properties of M(N)Ps, their integration in analytical methods opens new avenues for sensing and quantitative analysis. There is a large body of literature related to their synthesis, with a relatively small number of methods reporting the analysis of M(N)Ps using separation methods, which provide information on their purity and monodispersity. This review discusses analytical separation methods of M(N)Ps published between 2013 and June 2018. The analytical separation methods evaluated in this work include (i) field flow fractionation, (ii) capillary electrophoresis, (iii) macroscale magnetophoresis and (iv) microchip magnetophoresis. Among the trends in analytical separations of M(N)Ps an inclination towards miniaturization is moving from conventional benchtop methods to rapid and low-cost methods based on microfluidic devices.

Funding

Australian Research Council

History

Publication title

Trends in Analytical Chemistry

Volume

114

Pagination

89-97

ISSN

0165-9936

Department/School

School of Natural Sciences

Publisher

Elsevier Science London

Place of publication

84 Theobalds Rd, London, England, Wc1X 8Rr

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the chemical sciences

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